Reduced blood flow leads to:
Delayed wound healing
Injury
Increased infection risk
Higher likelihood of ulcers
In severe cases, tissue death (gangrene)
When neuropathy and PAD occur together — a common scenario in people with diabetes — the risk of serious foot complications increases dramatically.
Warning Signs in the Feet That May Reflect Cardiovascular Risk
Both the ADA and AHA emphasize that early recognition of vascular and neurological symptoms is essential.
Watch for:
• Cold feet or decreased temperature
May indicate reduced arterial blood flow.
• Swelling in ankles or feet
According to the AHA, persistent swelling (edema) can be a sign of heart failure.
Anatomy
• Leg pain during walking (claudication)
